The nation's three biggest drug distributors and a major drugmaker reached a $260 million settlement with two Ohio counties over the deadly havoc wreaked by opioids, just hours before the first federal trial over the crisis was about to begin Monday.

Wilmington Mayor Bill Saffo says, in the last 10 years, 243 people lost their lives in New Hanover County to opioids. 

An Oklahoma judge has found Johnson & Johnson and its subsidiaries helped fuel the state's opioid drug crisis and ordered the consumer products giant to pay $572 million to help address the problem.

From opioid addition to other highly-addictive drugs, the Brunswick County Sheriff's Office is taking a new approach to help people overcome illicit drug use.

U.S. overdose deaths last year likely fell for the first time in nearly three decades, preliminary statistics suggest.

The Columbus County Sheriff's Office says they arrested two people on narcotics charges, including one Whiteville City Schools employee.

A jury has convicted a Wilmington man on multiple charges in a car crash that killed a 2-year-old boy.

The trial of the man accused of crashing into a family's car and killing a 2-year-old continued Wednesday in New Hanover County. Jonathan Hayes was allegedly high on opioids at the time. 

Krista Turner started experimenting with dangerous drugs like hallucinogens when she was in her teens and her struggle with drug addiction continued about 10 years.